Health Life

New algorithm uses artificial intelligence to help manage type 1 diabetes

Glucose C6H12O6. Credit: Wikipedia.

Researchers and physicians at Oregon Health & Science University, using artificial intelligence and automated monitoring, have designed a method to help people with type 1 diabetes better manage their glucose levels.

The research was published in the journal Nature Metabolism.

“Our system design is unique,” said lead author Nichole Tyler, an M.D.-Ph.D. student in the OHSU School of Medicine. “We designed the AI algorithm entirely using a mathematical simulator, and yet when the algorithm was validated on real-world data from people with type 1 at OHSU, it generated recommendations that were highly similar to recommendations from endocrinologists.”

That’s significant because the people with diabetes typically go three to six months between appointments with their endocrinologist.

In that time, they can be at risk of dangerous complications if in their blood rise too high or fall too low. People with type 1 diabetes do not produce their own insulin, so they must take it continuously through the day using an insulin pump or through multiple daily injections. The algorithm developed by OHSU scientists uses data collected from a continuous monitor and wireless insulin pens to provide guidance on adjustments.

Paired with a smart phone app called DailyDose, the recommendations from the algorithm were shown to be in agreement with physicians 67.9% of the time.

The new study involved monitoring 16 people with type 1 diabetes over the course of four weeks, showing that the model can help reduce hypoglycemia, or low glucose. If left untreated, hypoglycemia can cause coma or death.

The engine was developed in a collaboration between the OHSU Harold Schnitzer Diabetes Health Center and the Artificial Intelligence for Medical Systems Lab led by Peter Jacobs, Ph.D., associate professor of biomedical engineering in the OHSU School of Medicine.

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Health article

New HPV test brings screening to your doorstep

Important research by investigators at the National Institutes of Health (NIH) and beyond has shown that the human papillomavirus (HPV) vaccine can prevent cervical cancer, which is caused by HPV.

And the latest NIH research has taken another important step in cervical cancer treatment: developing at-home HPV testing for people who may be at risk.

Sarah Kobrin, Ph.D., talked about this research and provided prevention information. Dr. Kobrin is the chief of the Health Systems and Interventions Research Branch at the National Cancer Institute.

What can you tell us about HPV vaccine research today?

There is more evidence now that the long-term effects of the HPV vaccine will benefit everyone.

– Sarah Kobrin, Ph.D.

The Centers for Disease Control and Prevention has been researching the HPV vaccine for about 15 years. They are constantly reviewing when you should be vaccinated, how effective the vaccines are, and who should receive them.

There is more evidence now that the long-term effects of the HPV vaccine will benefit everyone. The schedule of when people should be vaccinated may change from time to time. But this is because we are constantly learning more about the safety of the vaccine.

We hope to soon have Food and Drug Administration-approved home tests for HPV. People may feel more comfortable taking an HPV test in the privacy of their own home and mailing in a sample. This would make the process easier and more convenient for everyone.

What can be done to make cervical cancer prevention easier?

Awareness is a necessary first step. But awareness is not enough. In general, people are more aware of the HPV vaccine. The most important challenge is giving everyone access to it.

People have to actually get vaccinated and get regular cervical cancer screening tests, like the Pap smear and HPV