Health article

Methylmalonic Acid (MMA) Test: MedlinePlus Medical Test


What happens during an MMA test?

MMA levels may be checked in blood or urine.

During a blood test, a health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

During a newborn screening, a health care provider will clean your baby’s heel with alcohol and poke the heel with a small needle. The provider will collect a few drops of blood and put a bandage on the site.

MMA urine testing may be ordered as a 24-hour urine sample test or a random urine test.

For a 24-hour urine sample test, you’ll need to collect all urine passed in a 24-hour period. Your health care provider or a laboratory professional will give a container to collect your urine and instructions on how to collect and store your samples. A 24-hour urine sample test generally includes the following steps:

  • Empty your bladder in the morning and flush that urine away. Record the time.
  • For the next 24 hours, save all your urine passed in the container provided.
  • Store your urine container in the refrigerator or a cooler with ice.
  • Return the sample container to your health care provider’s office or the laboratory as instructed.

For a random urine test, your sample of urine may be collected any time of the day.



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