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Researchers discover AI can predict new atrial fibrillation, stroke danger

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A group of scientists from Geisinger and Tempus have discovered that synthetic intelligence can predict danger of recent atrial fibrillation (AF) and AF-related stroke.

Atrial fibrillation is the commonest cardiac arrhythmia and is related to quite a few well being dangers, together with stroke and demise. The research, revealed in Circulation, used electrical alerts from the guts—measured from a 12-lead electrocardiogram (ECG)—to establish sufferers who’re more likely to develop AF, together with these in danger for AF-related stroke.

“Annually, over 300 million ECGs are carried out within the U.S. to establish cardiac abnormalities inside an episode of care. Nevertheless, these assessments can not usually detect future potential for damaging occasions like atrial fibrillation or stroke,” stated Joel Dudley, chief scientific officer at Tempus. “This important work stems from our main investments in cardiology to generate algorithms that make current cardiology assessments, similar to ECGs, smarter and able to predicting future scientific occasions. Our purpose is to allow clinicians to behave earlier in the middle of illness.”

To develop their mannequin, the group of information scientists and medical researchers used 1.6 million ECGs from 430,000 sufferers over 35 years of affected person care at Geisinger. These knowledge had been used to coach a deep neural community—a specialised class of synthetic intelligence—to foretell, amongst sufferers with no earlier historical past of AF, who would develop AF inside 12 months. The neural community efficiency exceeded that of present scientific fashions for predicting AF danger. Moreover, 62% of sufferers with out identified AF who skilled an AF-related stroke inside three years had been recognized as excessive danger by the mannequin earlier than the stroke occurred.

“Not solely can we now predict who’s prone to creating atrial fibrillation, however this work reveals that the excessive danger prediction precedes many AF-related strokes,” stated Brandon Fornwalt, M.D., Ph.D., co-senior writer and chair of Geisinger’s Division of Translational Information Science and Informatics. “With that form of data, we are able to change the way in which these sufferers are screened and handled, probably stopping such extreme outcomes. That is large for sufferers.”


Synthetic Intelligence analyzing ECGs predicts irregular heartbeat, demise danger


Extra data:
Sushravya Raghunath et al, Deep Neural Networks Can Predict New-Onset Atrial Fibrillation From the 12-Lead Electrocardiogram and Assist Establish These at Threat of AF-Associated Stroke, Circulation (2021). DOI: 10.1161/CIRCULATIONAHA.120.047829

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Geisinger Well being System

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Researchers discover AI can predict new atrial fibrillation, stroke danger (2021, March 5)
retrieved 7 March 2021
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