Health article

Biomarkers recognized in collegiate athletes that would assist predict time wanted to recuperate from concussion

Media Advisory

Thursday, August 27, 2020


A collaborative research performed by scientists from the Nationwide Institutes of Well being, Division of Protection (DOD), and a number of tutorial establishments has recognized blood biomarkers that would assist to foretell which athletes want further time to recuperate from a sports activities associated concussion. This collaboration, often known as the Concussion Evaluation, Analysis, and Training (CARE) consortium, is supported, partially, by DOD and the Nationwide Collegiate Athletic Affiliation (NCAA).

On this research, performed at a number of websites throughout the U.S., 127 female and male collegiate athletes who had sustained a sports-related concussion had been examined at a number of time factors: shortly after damage, when their signs resolved, and one week after returning to play. Every athlete had additionally undergone preseason, baseline testing.

Utilizing an ultrasensitive assay that may detect minute quantities of protein, the researchers examined blood serum from these athletes and recognized two blood proteins that had been related to the size of time wanted by the athletes to return to play. Quantities of those two proteins, tau protein and glial fibrillary acidic protein (GFAP) had been discovered to be considerably completely different in athletes who wanted much less or greater than 14 days to return. Whereas additional analysis is required, the outcomes of this research are an necessary step in the direction of the event of a check that would assist predict which athletes want extra time to recuperate from a concussion and resume exercise.

This research was revealed in JAMA Community Open.


NINR Appearing Scientific Director and research creator Jessica M. Gill, Ph.D., R.N., FAAN is obtainable for remark.


CL Pattinson et al. Plasma Biomarker Concentrations Related to Return to Sport Following Sport-Associated Concussion in Collegiate Athletes – A Concussion Evaluation, Analysis, and Training (CARE) Consortium Examine. JAMA Community Open. 2020;3(8):e2013191. doi:10.1001/jamanetworkopen.2020.13191

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